Certain microorganisms with an incomplete citric acid cycle decarboxylate α-ketoglutarate to produce succinate semialdehyde. A dehydrogenase then converts succinate semialdehyde to succinate. These reactions can be combined with other standard

Certain microorganisms with an incomplete citric acid cycle decarboxylate α-ketoglutarate to produce succinate semialdehyde. A dehydrogenase then converts succinate semialdehyde to succinate. These reactions can be combined with other standard citric acid cycle reactions to create a pathway from citrate to oxaloacetate. Compare the ATP and reduced cofactor yield of the standard and alternate pathways. Transcribed Image Text: COO
COO
COO
|
CH2
|
CH2
|
CH2 NAD+
|
NADH CH2
|
CH2
|
Coo
CO2
CH2
C=0
H
COO
a-Ketoglutarate
Succinate
Succinate
semialdehyde